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(thymosin alpha 1)




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List of Tables
Table 1
Effect of Combination Therapy With Zadaxin (ZDX), Amantadine (AMN), and IFNα/β in Mice Infected With Influenza A Virus
  Table 2
Hepatitis B Clinical Outcomes (Intent to Treat)

List of Figures
Figure 1
Primary structure of thymalfasin.
Figure 2
Proposed mechanism of action of Zadaxin.
Figure 3
Serum woodchuck hepatitis virus (WHV) DNA in Zadaxin-treated and placebotreated animals.
Figure 4
ZDX in combination with AMN and IFNα/β increases survival of mice infected with influenza A virus.
Figure 5
Relapse time of B16 melanoma bearing mice treated with CY, IFN, and ZDX.
Figure 6
Effect of increasing doses of Zadaxin on tumor reduction in murine B16 melanoma.
Figure 7
Comparative adverse-event incidence.
Figure 8
Results at Chang Gung Memorial Hospital, Taiwan hepatitis B trial at 18 months.
Figure 9
Time course of complete response in the Chang Gung Memorial Hospital, Taiwan.
Figure 10
Results from the Italian hepatitis B trial at 12 months.
Figure 11
Pooled intent-to-treat analysis of end-oftreatment biochemical response.
Figure 12
Results in the US hepatitis C trial at 6 months.
Figure 13
Time to first ALT normalization in the US hepatitis C trial.
Figure 14
Results from the HIV trial in Italy at 12 months.
Figure 15
Clinical response to influenza vaccination.
Figure 16
Results from US influenza trial.
Figure 17
Antibody response to influenza vaccine with Zadaxin adjuvant in hemodialysis patients.
Figure 18
Zadaxin+TACE: HCC survival.
Figure 19
Effect of Zadaxin on metastatic melanoma.
Figure 20
Serum Zadaxin concentrations after a single subcutaneous dose (1.6 mg) of Zadaxin.

 



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