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ZADAXIN
(thymosin alpha 1)

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Introduction

ZADAXIN (thymalfasin), often referred to in medical literature as thymosin alpha 1 or Tα1, is a peptide that has been evaluated for its immunomodulatory activities and related therapeutic potential in several diseases, including chronic hepatitis B and C, acquired immunodeficiency syndrome (AIDS), primary immunodeficiency diseases, depressed response to vaccination, and cancer. The basis for effectiveness in these conditions is primarily through modulation of immunological responsiveness, as Zadaxin has been shown to have beneficial effects on numerous immune system parameters and to increase T-cell differentiation and maturation. This report summarizes data from clinical experience conducted with Zadaxin in over 3,000 patients in addition to studies conducted in vitro and to in vivo animal studies.